Unfortunately, your first example is what I've run into far too often. When you drop the size of an ebook by 100kb just by replacing all the span class options for just bold and italics to <b> and <i>, I go for dropping the bloat. So it seems it's still an ok option to use. I never redefine b or i for that purpose. The most I redefine are h tags at times because the default is just too large at times.
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