Most "western" comics and graphics novels are standard 8.5x11 page size, and since they are currently designed to be read in printed copy, often they contain 2-page panel designs, where the spread moves across two pages and then down (or in a big circle or any number on non-sequential layouts). Reading *.cbrs on even a 17" laptop can be frustrating.
Pretty much the point of reading comics/graphic novels is the interplay of story and art, and having to zoom around to see all of the art and figure out what the order is would just about kill the fun for me. Unless a comic has been designed to be read on a small screen or in absolute sequential panel-by-panel format, I'd pass on reading it on anything smaller than a larger screen.
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