I am having the same problem as Valky, and I have updated the firmware on my reader as well as my library software. I just checked, and my version of the eBook Library is 2.200.18100.
I also am sure I have the latest firmware update for my reader since I have deleted books from it.
Now, I did have to do the special way of loading the eBook library software using the special way of going to the command prompt since I run Vista 64 bit.
I have also loaded Adobe DE, and tried multiple things to get it to recognize my reader -- open Adobe DE after my reader is on and plugged into my PC, plug my Reader in after I open Adobe DE, etc. Nothing.....
Anybody have any other suggestions?