I haven't used Dropbox for this yet but now that I've upgraded to a 50GB plan, I might (only had 5GB before which I decided to dedicate to family photos/videos and personal documents). Recently been considering using CrashPlan.
For now, a nightly scheduled task for copying my entire calibrePortable install (using robocopy) to the home file server works. The nice thing about it is it's all self-contained. If the HDD in my computer crashes, I can just copy the calibrePortable install backup and I'll have all my settings, plugins, templates, libraries, etc.
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