Bah! Anime is a tool of the Debil! Da Debil I say! And as such I would NEVER make a recommendation.

Such as recommending:

Tokyo Godfathers: On a Christmas Eve, three Tokyo homeless -- mid-aged alcoholic man Gin, high school runaway girl Miyuki, and former drag queen Hana -- were searching dumpsters and trash bags for possible Christmas gifts for themselves, when cries from a baby drew their attention. Believing this was a gift from God, Hana, who couldn't have a baby of "her" own, vowed to take care of the abandoned baby girl and together they began searching for baby's mother.

or a series like:

The Irresponsible Captain Taylor: Justy Taylor has no training, no skill, no initiative, or leadership qualities; in fact, he has nothing going for him except one crucial thing: dumb luck. This is his only saving grace, and it saves him from impossible odds, time and again. By sheer accident, he rescues the General's beloved granddaughters; for which, the General is extremely grateful, and as such, makes this inept recruit a full Captain, but gives him command of the lowliest ship in the fleet, the Soyokaze. This ship has a crew of misfits and mutineers, so the General is not at all worried about Tylor making matters worse. He has killed two birds with one stone: he has given this inept freeloader a 'reward' for saving the granddaughters, and also put a captain in command of a ship and crew he would just as well see engulfed by a black hole. Thus, Taylor begins an adventure that takes him from the lowest and highest positions of authority, from which he somehow manages to make things turn out for the best.

Justy Ueki Taylor thought a career in the United Planets Space Force would give him an easy life: enlist, get a desk job, spend the rest of his life in quiet, boring comfort. No sooner does he take the qualifying exam than war breaks out with the Raalgon Empire, and circumstances quickly conspire to land this volunteer off the street in command of the cruiser "Soyokaze." Now Taylor faces two uphill battles - against the Raalgon fleet that wants to kill him, and against his own crew, who expect him to conform to some standard of military discipline. But as the war rages, Taylor's easy-going ways might have a better chance of converting his crew than vice-versa.

Or for those looking for a combination of romance and comedy:

Fruits Basket: Tohru Honda is 16 year old orphaned girl who gets invited to live in the house of her classmate, the handsome boy Sohma Yuki, and his cousins, 16 year old Kyo and 27 year old Shigure. However, these young men and parts of the rest of their family (both close and distant) hold a curse; if they are hugged by the opposite gender, they transform into animals of the Chinese Zodiac. Everyday is an adventure for sweet Tohru, as she gets to know everyone in the large family better (especially Yuki and Kyo), in both common and bizarre situations. But, the Sohma Family curse is certainly no laughing matter... it also holds horrible cruelty and heartbreak.
Yes, you'll never catch me recommending anime.

Yes, you'll never catch ME recommending any anime!