As a rule, no lithium-based battery should ever be allowed to fully discharge. Usually devices have circuitry to cut the device off before this happens, though. Li batteries work best and last longest with frequent shallow discharges and recharges, say allowing the device to go to 40% or so before recharging. Recharges don't need to be to 100%, either. LiON and LiPO batteries don't suffer from "memory" effects like Ni-based batteries. The old rules about fully discharging and fully recharging apply to nickel-based batteries--NiCd or NiMH (nickel-cadmium or nickel metal hydride), NOT to LiON or LiPO (lithium ion or lithium polymer). It is best to charge Li batteries often. Don't try to fully discharge the battery packs frequently. This only adds strain. Several partial discharges (regular use) with frequent recharges are better for LiON or LiPO than one total discharge.
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