Pretty much all epub viewers (barring very few in marginal devices) are based on (somewhat modified) webkit engines, so there shouldn't be any problem with rendering them. Also SVG support is IIRC mandated by the EPUB spec. As for positioning them, that is a bigger issue. You can always just insert the svg has an inline <svg> tag at the start of the closest element to the annotation position. Anything more sophisticated will probably require support from the viewing application.
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