I have a nook that reflows pdfs sold as ebooks. I have read a lot of them, too, because initially many of our Overdrive library books were only available as pdf.
It's clunky. You can get the text larger (generally you get to choose between microscopic, small, and HUGE), but there are always hyphenation* and page break problems, and sometimes the header/page number gets folded into the text. Images are an issue. If you're reading a pdf intended to be an ebook without much reliance on images, you can get reflow.
However, if your pdf has no underlying text or formatting, fuhgeddaboutit.
* the choice in hyphenation is between dropped hyphens and retained hyphens. Dropped hyphens are IMO infinitely preferrable. Retained end of line hy-phens can make the text near-ly unreadable.
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