As far as Canadians go:
If you like experimental literary fiction, I don't think you can go too wrong with Paul Glennon, whose intertwined short-story conceptual collection
The Dodecahedron, or A Frame for Frames was my introduction to the
Oulipo movement (probably best known for producing Georges Perec's novel written entirely without using the letter "e"). Disclaimer: I have not yet got around to reading his other books. It doesn't seem to be available as an e-book in English, but the French-language translation can be bought via Kobo (I picked it up just last month).
For multicultural mystery/crime novels, while I haven't gotten around to actually Donald J. Hauka's
Jinnah series, I did quite enjoy the CBC film adaptations of them, and they are available via Kobo, at least for Canadians, and I intend to get them at some point.
Don't know if he's available in e-books, but I've read a fairly good historical/literary novel by
Rudy Wiebe based on the doomed Franklin expedition with the lost ships Erebus and Terror (which some forum-goers may recall from the sale on Dan Simmons' version thereof).
And while I've only encountered a few of his works, I'd say that the late novelist & playwright
Timothy Findley is pretty good, especially his play
Elizabeth Rex which is available as a DVD from its CBC performance (out of print).
They may be a bit of an acquired taste, but I've always had a certain fondness for
Kristjana Gunnars' stories about the Icelandic-Canadian immigrant experience (will probably be really difficult to find outside of major Canadian metropolises).
ETA: for specific Canadian SF/F author recommendations, mine can be found in the
bottom of this post here in a thread where someone asked for Canadian SF/F, among other things.