I chose "on 24/7" as that is my habit with my primary computer. This machine is put into a "sleep" mode which powers down all accessories (via my intelligent UPS) every night and during the day when I'm out of the house.
My laptop is used much less frequently and it is turned off when not in use or put to "sleep" for short interruptions (meals, ...). My wife's notebook and deskop are also used less frequently and are turned off when not in use.
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