[crossi]

You could make something like the Frankenkindle keypad but instead of wiring in a physical big keypad use something like Dragon Naturally Speaking to send a signal to some device wired into the kindle keys.

I would be happy if I could use Speech Recognition on the kindle for PC. I can use it to open Kindle PC and to turn the pages but I cannot select or open the books with it. I wish either Amazon and/or Microsoft work work at making them fully compatable.

As for being a niche market that is true. There is a program called Zoom Text which magnifies and reads aloud computer screens. Because it is a niche product for the visually impaired it costs $700 but it is still produced and marketed. If you need something like that you need it and simply have to swallow the cost.