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As mentioned if you need to be able to use windows applications. The interface wouldn't exactly be ideal for a lot of those applications, but especially for something like excel you would want it. Though really, I'd rather sit in front of a desktop or laptop to run excel, but this and/or RDP to one of my windows boxes to run excel would be fine.
Some basic spreedsheets would run fine on an ipad or ipad2, but if you get in to heavy formula stuff like Monty Carlo simulations, an A4 or A5 chip does not have the grunt to handle intense math in any kind of resonable time frame. My basic Core 2 duo running at 3ghz can crank out something like 6-10x the processing power of the A5 in my iPad2...so a 60 second number crunching on my desktop would take something roughly like 10 minutes on my ipad2.
Of course, through online...at least right now, you don't have access to much other than the basic MS apps, so that limits the utility of what the extra processing power might get you.
Actual RDP though...I use that all the time on my ipad2 to connect to my server instead of RDP from my desktop or physically walking down to my basement, plugging the power cord in for the monitor and grabbing the keyboard and mouse down from on top of the machine when I need to do anything on the server.
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