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Each of us as individuals may need day and night, but we have many institutions that go about their business day and night. On a space station, ships would be arriving at all hours of the night. Their crews are going to want some place to spend their money, I would expect the Promenade to be open 24x7, especially on a space station where day and night are totally arbitrary.
I think that we would be safe from alien viruses, we would be too alien for a virus to infect. Bacteria are a different matter, they might pose quite a problem. We might be able to eat alien food, it would likely have the proteins, carbohydrates and fats that we need. But there might be nutrients that are lacking, or their could be toxins. For example, vitamin C might be unknown on some alien world, and we would have to bring our own. On the other hand, vitamin C might be a toxin to some alien species.
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