Generally, I prefer to read a book in print, or on an ereader which gves me as close an approximation to a printed pages as possible, and I don't like gimmicks in a book. However, sometimes it is possible to do non-traditional things in a book which actually enhance the reading experience.
I am currently reading Jennifer Egan's "A Visit from the Goon Squad", thanks to Robert Fulford's column
http://arts.nationalpost.com/2012/01...ut-the-timing/
Most of the book is presented in traditional novel format. However, an entire chapter is done as a PowerPoint presentation, and it works.
The only problem I found is that the PowerPoint chapter did not work well on an ereader, due to the small screen size and monochrome screen, but it worked very well on a laptop screen, so I can see where one might need occassionally to read a book on a tablet with a larger color screen