Some recent anthologies I've seen have included
"Rappaccini's Daughter" - Nathanial Hawthorne (I sort of have mixed feeling about what genre that might fall into)
Just read a story in the Pen/O.Henry Prize 2011 last night that is definitely SF based on global warming: Diary of an Interesting Year - Helen Simpson.
I wouldn't say either of those is a "favorite" as the OP asked but just thought I'd mention them in that it seems the SF/Mainstream category is shifting a bit.
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