Well, calibre will recognize it without further efforts, but you will have to define if you are going to load prc or epub into it (two different FWs, so calibre cant't guess
). And you don't need extra-tools for dust
And, if you want to purchase, yes, I'm afraid you need ADE (and register an address, it's easier that purchasing anonymous). You can register you Opus or use the cleaning tools before, your choice
And Opus is a very nice device, I agree, it was my previous reader and now it belongs to a friend's sister.