I have read on eInk and LCD devices for years. For nighttime reading, I use an iPhone or iPad. I use a custom setting for the background:
brown background
cream text
25% backlight
I can read for 3+ hours this way, with no eye-watering, bloodshot, etc. I may be able to read longer without the eyestrain, but 3 hours of reading puts me at about 2am, which means I'm a tired zombie the next day.
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