I have the same PRS+ version installed and not having any problems at all. You might try taking some canned air and blowing out the usb ports good, and check that no connection to them came loose inside.
I had a problem where only my 16GB flash drive wouldn't be recognized by my computer, 2, 4 and 8GB drives were no problem. I was convinced the 16GB flash drive was going bad. Double checked my computer and apparently I didn't fully snap the front cover on completely the last time I had it off (and where it sits it looked perfectly flush, not protruding at all), and that slight fraction of an inch difference didn't let the 16GB drive insert fully. It was one of those "smack myself in the head" moments after I realized the problem, so double check it all in case.
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