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As Billi says, the power used in sleep mode varies significantly between devices. The Amazon Kindle, for example, uses essentially zero power in sleep mode; you can leave it asleep for two weeks, and when it wakes up the battery level will be the same as it was when it went to sleep. Other devices do use a noticeable amount of power when asleep.
I don't think anyone knows the lifetime of an eInk display, other than that the oldest eInk displays, which are now about 6 or 7 years old, are still working just fine.
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