Well, you're comparing the two, so I'd think here's fine.
I'd say Calibre for everything except wifi. This means you'll need to set up everything anyway, but I'm not sure if it's possible to bypass Reader and just use Adobe - an expert will doubtless help any minute now...
'Course, if you have no need for the wifi, just stick with Calibre - and the occasional visit to a site called Apprentice Alf's Blog, which may be of interest. (Also sometimes known as the Black & Decker Admiration Society, in appreciation of its cleansing properties....
)
That's when you're happy and familiar with your T1, first, of course.