Haven't read too much on it yet, but I certainly am loving this thing!
I found that with Acrobat, I could reformat my technical manuals (MySQL, Linux, etc) by cropping out all white space and optimizing the PDF for a smaller file size. Once that is done, the manuals display very nicely on the reader and page turns are relatively quick. The TOC still work as well, which is wonderful for a technical manual. I'm pleasantly surprised that I was able to make these work so well!
I'll definitely report more later.