Someone had this issue with calibre on OS X a while back, unfortunately, I can't remember how they resolved it. Try googling for OS X calibre comments not visible or something along those lines. Simple thing to try is changing your interface font in Preferences->Look and Feel in calibre.
As for the unknown symbol in downloaded metadata, thats a character encoding issue, post the title author of a book that displays it and also what metadata sources are you downloading from.
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