How so? I am serious. Just what about the delivery as a digital file to be viewed on an e-book reader, or for that matter just a tablet or computer monitor will greatly change how one thinks about literature?

I can see that ebooks (with the book designation a question mark) will provide sort of one format shopping for everything from something like War and Peace to a collection of some celebrities Tweets, but that is not changing thinking about literature. War and Peace will still be literature and Ashton Kutcher's Tweets will still be what those are.