I feel like such an outcast lol.
I've never liked E-Ink at all. I started reading on the Rocket and then the REB-1100 which had backlit LCD screens and I've never wanted to go back. I read now on my phone using the Kobo app while I wait to decide which ereader/tablet I end up buying.
I don't find any issue with eyestrain and I'm a voracious reader. Probably a minimum of an hour or two a day for the last almost 14 years.
I don't know how people stand the page turn 'flash' on E-Ink, and I know I can't live without being able to read in low light situations. I'd say that probably 70% of the time I'm reading in light levels that would require a supplemental light source if I was using E-Ink.
I like the look of the E-Ink on a page, don't get me wrong. I'd like to see a hybrid system that figures out a way to backlight the E-Ink page or switch from LCD to E-Ink depending on the active app.
The rest of my family seems to go along with my lead as well. My wife, father, mother, and even a few friends have used the REB/EBW units exclusively for probably a decade at least and have never complained about eyestrain. We're all moving towards tablets or Vox type tablet/ereaders now.