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It all comes down to pixels per inch. At a high enough resolution, LCD is perfectly comfortable for reading (though I do recommend reading white-on-black rather than the usual black-on-white). Most people are most familiar with reading on their 100ppi or less PC monitors or their 132ppi iPads, both of which are painful. At least for me, anything above 150-160ppi is comfortable and causes no eye strain. I read almost exclusively on my old iPhone 3GS (320x480 3.5" screen, which is around 165ppi) and now on HTC HD7S (480x800 4.3" screen, or around 212ppi). For people who find phones too small, the Nook Color's 1024x600 7" screen (170ppi) is still above the comfort minimum.
Just from my own empirical experience, I ignore any "backlights give me headaches" arguments. There are other complaints that can be leveraged against LCD screens if you really want to hate on them (battery life, low ppi at higher screen sizes, small screens on phones, they're often multi-function devices that provide too many distractions away from reading like checking MyFaceSpace or playing Angry Birds, etc), there's no need to make up headache concerns.
Or maybe everybody's really complaining about iOS iBooks which still does not have a proper night/white-on-black reading mode.
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