^^ I'm the OP and I'm jumping into the Bones discussion
IIRC the Temperance in Bones is a fictionalized version of Kathy Reichs. She's an anthropologist who who's also a mystery author who writes books about a character named Kathy Reichs. I haven't followed the show since the second season though.
@alanspace: I've actually sampled Women's Murder Club (both book and show) I don't think it really fits what I'm looking for. I put Holmes and Monk in the OP for a reason. I'm looking for a female character in that tradition.
Now that I've thought about it I think reading about the new show 'Unforgettable' was what got me thinking about this. I've read some reviews/comments that mention that the show didn't really show how messed up a person with perfect memory can be. It got me wondering if there's a lady-Monk character out there.