[AprilHare]

I think I've become a lot less vocal about how I'm enjoying my ebook reader.
I read Mistborn lately; it was inspired by a friend who expressed an interest in it, but didn't have it in ebook format (legally). I provided it for her and we read it; me on my Sony Reader, her on her Kindle.
She is vision impaired (limited field of vision, short sighted and one eye) and enjoyed the larger font sizes - but later on stated she preferred it on a computer screen in PDF format, partially due to comfort, partially due to a desire for ligatures.
What do you think? Is the ebook reader good for people with strong vision impairment, or is there more we can do?
I never have concentrated on the lack of ligatures. Do any of the ebook formats or readers support ligatures?