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For large bodies of text reproduced at high quality (i.e. greater than 120ppi for arm's length reading) serif faces are generally more readable. On the other hand, single lines of a few words (e.g. headings, wall signs, ...) and san serif is easier to read quickly. When arm's length display is relatively low resolution (e.g. almost all CRT and many LCD displays), serifs fail to render well making san serif preferable.
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