This manufacturer of external hard drives recommends disconnecting the device before unplugging it: 
 
 
Repeatedly inserting and removing a USB device may stop the USB port from responding: 
 
   Shutting Down SimpleDrive on Windows PCs 
   1. In the System Tray, double-click the Safely 
 Remove Hardware icon. 
 2. In the Safely Remove Hardware window 
 that appears, select SimpleDrive, then 
 click Stop. 
 3. When Windows notifies you that it is safe 
 to do so, unplug SimpleDrive from the 
 computer’s USB port. 
 
   Shutting Down SimpleDrive on Macintosh Computers 
   1. Double-click the SimpleDrive 
 desktop icon. 
 2. In the Finder window that appears, 
 click the SimpleDrive Eject button. 
 3. Unplug SimpleDrive from the 
 computer’s USB port. 
 Repeatedly inserting and removing a USB device may stop the USB port from responding. 
 Once the port is in this state, it will no longer recognize any USB device.  
 
So I think this is advice to be followed when disconnecting the Iliad, Kindle, Gen 3 or Sony or whatever so that the USB port does not become corrupted. 
		 
		
	
		
		
		
		
		
		
		
		
		
		
	
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