Adobe recently released a preview for a new ADE version.
Among other things, they switched to .net, causing ADE not to work with wine anymore.
I posted a message there :
http://forums.adobe.com/message/3839931#3839931 (You might need to be logged in adobe's message board)
Response was the usual : we don't support linux.
If you're using ADE with wine, and I know there are a few linux user around here, please post on the adobe message board, to tell adobe there are people using Linux who would appreciate a working software.