Here are the requirements for the Sony Reader Library, which says it should be compatible with 10.4.11.
Quote:
Mac System Requirements
OS: Mac OS X (32bit) : 10.6.2 or later, 10.5.6 or later, 10.4.11 or later
CPU: Intel, PowerPC G3, G4 or G5 processor
RAM: 128 MB or more
HD: 80 MB or more
Monitor: High Color or more, 1,024 x 768 pixels or more
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Perhaps if you are more specific about your problem someone can better help you. Does your Mac recognize your 600 as a device when you connect by USB? Is it just the Reader Library which doesn't work? Is it running ok & just doesn't recognize your 600? Or, does Reader Library not even load properly and you have some strange behavior like only the menu bar showing?
Some people have had success just by changing the language preference to "US (computer)" under system preferences. You could try to remove and reinstall the software following Post #5 in this thread link.
https://www.mobileread.com/forums/showthread.php?t=78921