Actually, what's most important IMO is not the techie debate about what format or DRM, etc. but the prospect that mega-authors might routinely opt of the publishing process altogether and offer their books directly via the web.
Now a few indie authors have done this, generally in partnership with Amazon and the major booksellers, but generally they are the minnows of the publishing world (no disrespect intended).
It would be different if Nora Roberts, James Patterson, or Stephen King started offering their works directly via websites which they set up,a la Pottermore. (They could do mobile apps, too, I suppose). That's a huge chunk of the income of major publishers and booksellers.
This would be a much bigger deal than Amazon going ePub, and would reshape the book industry in ways that I at least can hardly imagine.
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