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They explain that in Star Trek Enterprise. The klingons were experimenting with a formula to make super klingons. The formula was originaly used to make Khan and his people so it ended up having human dna in it. When the klingons started dieing because of the stuff they kidnapped a doctor who eventually found a cure ..the problem though is that their appearance was altered and it took several generations for it to clear up. According to Worf the klingons find the whole thing VERY embaressing and do not like to talk about it . There you go that should help.
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