Thanks for the swift reply...
1) - none of those things helped, but debug-mode showed something, details below.
2) - thanks, that's better!
So, my computer has something slowly killing it, at the moment it's super-sensitive to memory leaks. Anything that is leaking kills it eventually. That's what happened here, a reboot means I can run calibre again. But it didn't show the error message that I get from any other app before it died, it just dissapeared on me. (Debug-mode showed the error). This may not be the best result from an error-handling point of view... The memory leak probably isn't in Calibre by the way (or at least, isn't necessarily in it) - killing Calibre was just a symptom.
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