I've used
MindManager at work and it's pretty great. There's an add-on that meshes with the
Getting Things Done techniques, but I haven't had a chance to try it. We use it primarily for brainstorming, which it is great for, and organizing tasks related to a project. It links with Outlook and Project, which can be a boon. I don't think we use it at all to its potential, and I've been trying to dig into it a little more.
I hadn't heard of the
Personal Brain before. I might have to give that a try. I'm always working on so many disconnected projects and juggling so much information, that it may help me at least speed up access to info, if nothing else.