I routinely read 2-column scientific papers on my full sized eDGe and they look very good. I usually have to zoom in a couple levels to make reading more comfortable but not enough to force panning to read the page. Highlighting is the main problem, as there are some bugs in Adobe's software that causes some serious headaches when you try to highlight text on PDFs with complex formatting.

Data moving is very easy, especially if you make use of dropbox.