I read alot of .pdf textbooks on the eDGe. I take alot of notes. What works for me is that I reversed the screens, putting the eInk side on the right (I am right handed). I open books on the LCD with RepliGo (as suggested by cheyennedonna) and then take notes on the eInk side as a journal. It works extremely well. The downside is that I cannot annotate the books directly, but I dont care about that. Reading and taking notes simultaneously is excellent on the eDGe. To take it one step further, it is also great to email the .pdf to myself and then import it into a Microsoft OneNote notebook.... but thats just me. I am a major fan of OneNote and use it extensively.