A PDF is a PDF, so the answer would be yes, as cheyennedonna indicates.
I have a Livescribe pen (which I don't use since I have an eDGe). You can't connect the pen to the eDGe, of course, but if you upload the pen contents to the desktop app and export to PDF, then the resulting PDF is useable on your PE. If you're uploading from the large 8.5"x11" notebooks, the issue you'll have is that the PE screen is very small, so the 8.5"x11" PDF generated by the LiveScribe Desktop app will be tiny. You can zoom in and pan around, though, but you may find this tedious. This is where the larger eDGe is better suited for working with letter-sized PDF documents. If you're uploading from the smaller half-size notebooks ("journals"?) then you may be able to read the PDFs without zooming.
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