Touch for me all the way. I wanted to physically turn pages with my first button only reader and tapped and swiped the screen all the time. This is why I bought the Sony. It is reading bliss. No fingerprints, you can choose in which direction you wanna swipe and it is ultra responsive. Double tap opens your preferred dictionary... I read one handed all the time, even though not all my books are of the one-handed kind
Never ever would I go back to any button operated reader. If there were no IR-touchscreens any more, I'd rather go back to pbooks.