Though you mentioned that you have no preference over LCD or E-ink, you may want consider the difference. I have a Kindle, but I fell in love with the E-ink display before I even noticed the other features. The Kindle and the Sony line have Pearl displays, but from in-store demos of other readers I've seen, E-ink looks great whether it's Pearl or not. I
love my Kindle, but I think I probably would've been just as happy with the display of any other E-ink device.
You may already be familiar with Calibre, but it's worth mentioning that no matter what your device, if you're using Calibre, there's very little you can't do as far as making your books look great and making any format compatible.
As an aside, judging by your user name, you may want to consider that the Kindle version of
Dune is horribly formatted.
Good luck and happy reading!