The Stand by Stephen King - Captain Tripp (the plague) starts as a summer cold. I caught a cold right after I started reading it. Had to put it down. Couldn't pick it up again for a long time.
More recently - Hunting Julian by Jacqueline Franks. I really liked her previous books but this one was very disturbing. I was very creeped out by the guy and how he seemed to feed off of the sexual energy of women. The first time the couple had sex it felt like he was "mind raping" her and I quit reading it.
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