I upgraded from a 505 to a 650 last December. I loved my 505 and was very reluctant to change it, but I am sooo glad I finally did. The improved screen and (particularly) the vastly better refresh times of the 650 improve the "reading experience" no end.
Assuming it's the right size screen for you, go for the 650 unless you're seriously constrained financially, in which case grab a 505. I think the 600 was the generation to avoid.
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