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My only experience is with the Kindle.
Pros: You can definitely change the font size, space between lines, etc. to make the text more readable. And if your mother wants to use the tiny keyboard, well, there are tiny raised dots on the F and J keys to help people work out which key is which.
Cons: You can't enlarge the text on the various menus, unfortunately. The homepage menu is fixed in size, and if your mom wants to change the sort order, she'll have to peer at the menu line at the top [Sort by... Most Recent First, etc.], which could be challenging. If the displays could be customized, and not just the e-texts, the Kindle would be vastly more accessible to people with vision problems.
Also, your mother's mileage may vary, but many elderly people have dexterity issues - difficulty with the fine motor skills required to make small, precise movements with the fingers - that could make entering text on that tiny keyboard a pretty big challenge. I know that my late dad could never have managed it :-(
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