Thanks much, Manichean--problem solved! I'm not sure which of your suggestions did the trick, however. I haven't put a new PDF on the Kindle for over a month, but I tried disabling the plugin, and the contents of the Kindle came up in maybe 5 minutes. I then ejected the Kindle, re-enabled the plugin, and reconnected the Kindle, and the contents came up in about 15 seconds. Probably a file got corrupted and Calibre needed to reread everything from scratch.
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