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2. It depends on your reading program.
Coolreader has all colors as background. (drm free epub, fb2, txt and probably more formats).
Adobe kind of sucks, but you can mark all the text, thus making the background around it blue. Might be better, might be worse, you have to see for yourself.
Soft colors are (for me) dark orange, blueish (like the dark blue on this forum), something like that. If the screen is bright, what you want is to actually reduce the contrast between text and background, so it will be easier on the eye (my theory). Grey might also work.
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