Hi, I had the same thing with my prs-650, basically it locked up with "OPENING BOOK" and only 1/2 the lines were displayed..
I tried soft reset, hard reset.. when i connected it to my laptop the "CHARGING BATTERY" didnt appear like usual, but i could still access the flash storage on the reader via USB cable..
I sent of an email to sony support, and they said to send in for warranty replacement..
After a week of sitting in a box waiting for me to get around to sending to sony, i decided i would post it off, but first delete all the books and notes i had on it.. After being plugged into my laptop via USB for a couple of minutes the "CHARGING BATTERY" message came on, screen was still messed up. I unplugged from laptop, switched on, and it started working, screen still not perfect, but after a reset a couple of times, everything is working perfectly again..
I wonder if its a fault with the reader, software problem..
see pics for what the screen looked like..
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