If it weren't for the fact that B&N is running them into the ground, Fictionwise would be my favourite store to actually buy from*.
Shopping cart which clearly shows whether discount pricing has been applied, wishlist, frequent major % off coupons that can be used in conjunction with another sale going (such as the 15% off weekly new releases), allow Paypal as well as credit card — all on top of a fairly good catalogue of DRM-free MultiFormat backlist sf/fantasy by authors I actually want to read!†
But they've stopped sending me the newsletter with the discount codes, removed ePub as an option from their Secure formats, and have this nasty habit of purging from their catalogue titles I had in mind to buy for what seems to be no apparent reason, given that a lot of this stuff was put there by small presses/the authors themselves who still have their other works from the same imprints going.
Aargh.

I blame B&N, who've taken away much of the useful things about Fictionwise that people liked (Micropay rebates, magazine subscriptions, etc.) and replaced them with a nice big Nook advertising banner at the top, and links to the B&N eBook store pages at the bottom.
* Amazon works better for browsing, due to downloadable samples which more-or-less reflect what the actual e-book version formatting will be like. But I really dislike paying for Mobi/Topaz, and will only do it if the book is dirt cheap at a price not available elsewhere and I can pay for it with my Swagbucks earnings..
† I love the idea of Baen's Webscriptions, but the actual backlist which gets included is a little lacking, for my tastes. Needs more Subterranean Press offerings.