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It is very important to make sure you only ever install one active (real-time) AV application at a time. Installing more than one can cause serious problems and instability on the computer.
I use Microsoft security essentials for my primary AV, and malewarebyte's Anti-Maleware (also free) as an occasional backup, as it only does manual scans. Maloware is also the first tool I install whenever removing viruses from an infected computer and it is very effective at removing just about anything.
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