You dont need ADE loaded to have Calibre recognise your reader but you will need it to download books with DRM content.
Have you got any books in Calibre?? that might be why it doesnt recognise your reader.
There are a number of free formatted books on the forum in both Epub or LRF (for Sony) which you can download (see Ebooks in the header above) and then you can transfer to Calibre
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