Yes, even for PDF books. The problem is that the Kindle, almost uniquely among eInk readers, has absolutely no support for PDF reflow. Since most PDF books are formatted for a much larger page size than a 6" screen, the only way to read them is to zoom in, and then pan across the page, which is painful in the extreme. That's why you've heard of people e-mailing their PDF documents to Amazon's document conversion service, to convert them to Mobipocket format.
If reading PDFs is high on your priority list, I'd look at something like the Sony Reader instead; it has enormously better PDF support than the Kindle does.
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